Hemp CBD oil side effects – What are they?


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Hemp CBD oil is considered legal across the states but have you had any side effects as a result of using it? I can tell you what I gained from research and from my past experiences the answer is yes, but it is very minimal. So let’s explore Hemp CBD oil side effects and see what they are.


Hemp has been utilized for different purposes since it’s been discovered. Everything from creating clothing, skin care products, food, plastic and more. The possibilities are endless with what we can do with this amazing plant.

As for side effects of using hemp, it’s difficult to find anybody who has reported any casualty or significant ailment from utilizing CBD hemp oil, there are some reports of side effects, however.

But now that CBD hemp oil is legal across the U.S and Canada that can make way for a lot of shady products coming through and the way it is processed could be bad as a result. Below are some examples of reported side effects from the use of hemp CBD oil.

Upset Stomach 

Stomach Upset Side effect of CBD OIl

Talking with various individuals and from past experiences, it appears that the most widely recognized report of using hemp CBD oil is a mildly disturbed stomach when taking it in bigger dosages. Even still, only a small amount of people report of this problem. However, the stomach disorders are usually mild and don’t last for long.

Emotional Disturbances

Depression can be a side effect of CBD oil

There are other studies out there that have shown that other negative symptoms of using CBD hemp oil are present when taken in high measurements. The complete opposite of what you are going for.

I myself, have experienced this where I experienced anxiousness from my CBD oil but noticed it would only appear if I took too much. Since I am hypersensitive to any type of supplement it didn’t take much to push me over the edge. A good reminder to note when taking the oil is that everything should be taken in moderation.

When using a high amount you could open yourself up to issues, and what I mean by high amount I mean about 2,000mg of CBD or higher. A great number of people typically take about 3 and 20mg at any given moment about 3 times a day. It is a good starting point and everyone metabolizes it differently so you find what works for you.

Lack of Sleep

Another negative maybe the lack of sleep, which can be a side effect of taking too much CBD Oil. This is the reason individuals with sleep problems report positive outcomes when taking CBD Hemp Oil. However, for the individuals who, for reasons unknown, get the opposite effect. Essentially CBD hemp is supposed to relax you and help you sleep but to some, it is quite the opposite.

Interference with other drugs or medications

According to NCBI, [1] drugs and other chemicals are usually metabolized in the liver in the drug-metabolizing enzyme system.  CBD hemp oil (cannabidiol) when ingested particularly can inhibit the effectiveness of certain drugs. CBD can indeed interact with a series of pharmaceuticals, as it inhibits the activity of some liver enzymes called cytochrome P450. This family of enzymes metabolizes most of the pharmaceutical drugs used to treat humans. If one takes high doses of CBD, the cannabinoid can temporarily neutralize the activity of P450 enzymes and thus alter the way drugs are metabolized inside the body.

This action of CBD can be regarded as a side effect, but it’s not always a negative trait, as the deactivation of P450 enzymes is one of the mechanisms through which CBD neutralizes THC as well.

This review paper on the safety and the side effects of cannabidiol[2] by the NCBI, for example, suggests that controlled cannabidiol administration is safe and non-toxic in humans and animals.

However, if you are taking pharmaceutical drugs and wish to take CBD, you should discuss any potential complications regarding reduced P450 enzyme activity with your doctor and/or pharmacist.

Dry mouth

Having an unpleasant dry sensation in the mouth is another side effect of CBD hemp oil. This impact is by all accounts caused by the association of the endocannabinoid system in the inhibition of saliva secretion. Cannabinoid receptors (type 1 and 2) are available in the submandibular organs which are in charge of creating salivation. The enactment of these receptors changes the salivary production, prompting mouth dryness. Dry mouth will practically make you dehydrated, so it’s always good to take it with fluids.

Low blood pressure

Higher measurements of CBD hemp oil may lead to a fall in blood pressure, which can happen inside a couple of minutes after CBD enters your system. This fall in blood pressure is frequently connected with a feeling of dizziness. If you take medicine for blood pressure, then you have to consult with your doctor prior to taking CBD.


With low blood pressure may come with the feeling of lightheadedness. This symptom of CBD hemp oil is can frequently be settled by drinking some tea such as liquorice root.


CBD hemp oil can lead to drowsiness when taken in higher amounts some claim. For those experiencing this, you have to stay away from machinery and vehicles when using it.


All and all these side effects are usually caused by a result of taking too much CBD hemp oil, or a bad batch of oil.

You can chalk it up to most of these side effects are anomalies but they still should be considered. The key is to start off slow and take small doses at first and then work your way up. There are many more benefits to using Hemp Oil than there are cons.

It is important that you do your research when looking into a good supplier when buying CBD Hemp oil. Quality does matter, ensure you are getting your product tested by a 3rd lab party to ensure there are no biases and to make sure you are getting a good high-quality product.

I hope you found this information about the side effects of CBD Hemp Oil useful. Have you experienced any side-effects like the ones listed above? Feel free to share your comments!


  1. https://www.ncbi.nlm.nih.gov/pubmed/171822
  2. Safety and side effects of cannabidiol (NCBI/NIH)
  3. https://elixinol.com/blog/known-and-potential-side-effects-of-cannabidiol-cbd

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